While most legions have fairly obvious set ups from their unique RoWs giving them massive bonuses in one thing, I think there's a place in Heresy for the Legions Astartes rules being unexpectedly good at some RoW resulting in some weird and wonderful lists.
For example, Sons of Horus reserve rolls and extra attack from very bulky makes them excellent at sky hunter phalanx. Similarly, Night Lords get 3+ jink and +1 to wound.
Alternatively, Iron Warriors lack of Pinning/Morale from shooting makes Recon Company/Assault Marine RoWs good. Iron Hands -1 to hit makes them tricky to dislodge as well.
Personally, I run a Emperors Children Sky Hunter (way worse than White Scars!) and a World Eater list that is geared towards shooting (they're as good at it as anyone else then angry after!)
What weird RoWs/Strategies do you run?